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Fast Track Diagnosis of Skin Cancer by Advanced Imaging Technologies and...

Conditions :   Skin Cancer;   Malignant Melanoma Intervention :   Diagnostic Test: Reflectance confocal microscopy (RCM), Photoacoustic imaging (PAI) and tape-strippng of RNA and lipids Sponsor :...

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Comparing Conventional Grid Laser Photocoagulation and Subthreshold...

The prevalence of diabetes mellitus has increased significantly in Hong Kong for the past decade [1]. Diabetic macular edema is one of the most common causes of vision loss in patients suffering from...

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Synergy Between morpHOlogical and inflammatoRy Evaluation in Predicting...

Data from human autopsy studies have showed that thrombosis of a ruptured plaque with a large necrotic core, inflammatory cells and a thin fibrous cap, the so-called thin cap fibroatheroma (TCFA),...

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Feasibility of Middle Ear OCT Imaging

Rationale: Various middle ear diseases can affect anatomical structures of the middle ear in different ways. Unfortunately, current methods for assessing the structure and function of the constituents...

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Quantitatively Analysis of Fundus Structure Characteristics in Glaucoma...

To quantitatively analyze the fundus structure and microvascular characteristics of GFCS and non-GFCS (NGFCS) using optical coherence tomography angiography (OCTA), to explore the vascular-structural...

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The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of...

Topical Brimonidine is a well-established topical antigalucoma, ocular hypotensive therapeutic that has been in use since 1996. Brimonidine stands out among other topical ocular hypotensives in that it...

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Comparison of OCTA Factors in Patients With or Without Amyloid Pathology: A...

To compare alternation of retinal microcirculation within the macula and optic disc in patients with dementia, mild cognitive impairment (MCI), and cognitively healthy subjects who had positive amyloid...

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OCT Evaluates the Effects of CTEPH Treated by Scoring Balloon

Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease of obstructive pulmonary artery remodelling as a consequence of major vessel thromboembolism. The diagnosis of CTEPH is based on...

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The Cohort Study of Pediatric Cataract

This retrospective-prospective bidirectional cohort study aims to observe ocular parameter changes, different surgical/vision recovery strategies and postoperative adverse effects among young children...

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PREcise Percutaneous Coronary Intervention for Stent OptimizatION in...

There has been ample evidence of the role of intracoronary imaging for optimizing the stent, especially among the patients with complex coronary lesions. Intracoronary imaging can be used during the...

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A Study of Observation and Follow-up in People With Basal Cell Carcinoma

The purpose of this study is to find out more about how Basal Cell Carcimonas/BCCs grow and to learn more effective ways to monitor and treat these common cancers. This study will not provide any type...

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The Effects of Glycerol as an Optical Clearing Agent for Visualization of the...

This study will examine the improvement in middle ear optical coherence tomography imaging from the topical application of glycerol to the tympanic membrane in normal, opaque and post-operative ears

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Intraoperative OCT Guidance of Intraocular Surgery (MIOCT)

Optical Coherence Tomography (OCT) is used to capture reproducible ocular morphology and cross-sectional tissue measurements in-vivo in a rapid, non-invasive, non-contact manner. It has displaced...

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Repeatability and Stability of Healthy Skin Features on OCT

Optical coherence tomography is a non-invasive scanner which generates real-time in-vivo images of the skin and its adnexal structures. Images are generated by light-interferometry.

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Comparative Study of High Performance Low-Cost Optical Coherence Tomography

The purpose of this study is to complete performance testing of our custom optical coherence tomography (OCT) device to verify it can deliver retinal images of similar quality to a commercial OCT device

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Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis

Stroke was the second leading cause of death worldwide and the leading cause of death in China in 2017. ICAS accounted for 10% to 15% of ischemic stroke in Western countries, and as much as 46.6%in...

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Assessment Of Diabetic Maculopathy Changes After Phacoemulsification by Using...

Diabetic patients pose a particular challenge because of the tendency for early formation of cataract in them and propensity to develop macular edema after cataract surgery. Macular edema (ME) is a...

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Comparison of Results Achieved by Different Ballooning Techniques in...

Single-stent strategy with provisional approach represents the gold standard for percutaneous coronary intervention of bifurcation lesions, and, according to European Bifurcation Club, performing...

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Imaging Retinal Vasculature in Infant Eyes

Retinopathy of prematurity is a leading cause of childhood blindness worldwide. The fovea, a critical location in the retina determining visual acuity and visual function, and the blood vessels around...

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Optical Coherence Tomography Angiography Criteria Of The Choroidal...

This study aims to compare choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia.

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Multimodal Equipment for Teleophthalmology Assessment (META)

We have developed a Multimodal Equipment for Teleophthalmology Assessment (META) device. This novel device is compact, portable and suitable for packaging and express delivery. With this device, there...

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Optical Coherence Tomography Angiography (OCTA) to Assess Cardiac Output and...

Around 3500 children including 1,000 babies a year in the UK require heart surgery. Open-heart repairs involve the heart being stopped, while blood is pumped around the body using a cardiopulmonary...

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Subthreshold Nanosecond Laser for Non-resolving Central Serous...

This is a prospective, multicentre, sham-controlled, participant- and assessor-masked superiority trial with two parallel treatment arms which aims to investigate the safety and efficacy of...

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Added Value of OCT for Diagnosing Recurrent BCC After Non-invasive Treatment

Superficial basal cell carcinoma (sBCC) can be treated non-invasively, but follow-up is necessary because lesions can reoccur. This study aims to evaluate the additional value of optical coherence...

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Prediction of Progression of Retinal Ischemia in Diabetes

x Diabetes Mellitus (DM) is a major public health problem with significant socioeconomic implications due to its increased prevalence. Diabetic retinopathy (DR) is the most frequent complication in DM...

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Feasibility and Safety of Hybrid IVUS-OCT System

Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) were all recommended for percutaneous coronary intervention (PCI) optimization in the latest guidelines, however, which imaging...

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Treatment of Functionally Non-significant Vulnerable Plaques in Patients With...

The study aims to compare a preventive percutaneous coronary intervention (PCI) plus optimal medical treatment (OMT) strategy vs. OMT for treatment of non-functionally significant non-culprit lesions...

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Structural Description of Skin Biopsies With Dynamic Full-field Optical...

Basal cell carcinoma (BCC) are the most frequent skin cancers. Their incidence is constantly increasing. BCC diagnosis is first clinically suspected and then confirmed following histological...

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Prevention of Onset and Transition to an Advanced Form of Diabetic...

Diabetic retinopathy, or damage to the retina caused by diabetes, is one of the most common complications in all patients with newly diagnosed diabetes mellitus of both types. These are mainly...

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Validation of Interleukins and Other Cytokines Together With OCT Imaging for...

As conventional corneal scraping with bacterial culturing has several disadvantages such as long duration until diagnosis, invasiveness and lacks alternatives, there is demand for a novel non-invasive,...

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Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis

The retinal vessels have been shown to reflect vascular changes inherent to systemic pathologies, even when no ocular disease is identified. As such, the eye's vasculature is ableto serve as a window...

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Correlating the Measure of Retinal Vascular Density Through Angio-OCT With...

Recent case-control studies have proven that the retinal vascularization mirrors the cardiac vascularization: more the coronary network is altered, more the density of retinal vessels is reduced. No...

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Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical...

Banff classification stands as gold standard and international consensus for the identification, diagnosis and categorization of renal allograft pathology. In addition to multiple revision dedicated to...

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Training Health Care Professional in Detecting BCC on OCT Using E-learning...

In this study, various health care professionals will follow an E-learning module in which BCC detection on OCT is explained. Thereafter, the participants will test their skill by assessing OCT-scans....

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All Eyes on Pcs - Analysis of the Retinal Microvasculature in Patients With...

The investigators will recruit patients with PCS, fully COVID-19 recovered participants and COVID-19 infection naïve participants. After comprehensive clarification and given written informed consent,...

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Retinal Microvasculature by OCT Angiography During Integrating Physical...

Diabetic retinopathy is a common condition of diabetes and can lead to blindness, making it one of the most feared complications of diabetes. Recently, it has been proven that the parameters measured...

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Retinal Vascular Manifestations in Patients With Common Internal Diseases on...

Hypertension, diabetes mellitus, and dyslipidemia are common internal diseases, and all diseases are atherosclerosis risk factors. Previous studies applied color fundus photography to analyze retinal...

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Evaluate the Safety and Efficacy of Intracoronary Lithotripsy Balloon...

This is a prospective, multi-center, single-group target value clinical trial, which will be carried out in many clinical trial institutions in China. A total of 184 subjects (70 of them are OCT...

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Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19

The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is affecting almost all countries in the world and because of its worldwide spread has...

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Histopathological Analysis of Temporal Artery Biopsy Following Dynamic...

Giant cell arteritis (GCA) is a type of large vessel granulomatous vasculitis responsible for the inflammation of the aorta and the branches of the external carotid, notably temporal arteries. The...

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